Your Legs Are Screaming "HELP!": 5 Warning Signs from Your Liver

3. Severe Itching (Pruritus)

Itching that won't go away—especially on the legs and feet—can be a sign of liver problems.

Why it happens: When the liver struggles to process bile, bile salts can build up under the skin, causing intense itching. This itching is often worse at night.

What to look for:

  • Itching without a rash

  • Itching that gets worse at night

  • Itching on the palms, soles, or legs

  • Scratching that causes skin damage

When to worry: If itching persists despite moisturizing, or if it's disrupting your sleep, talk to your doctor.

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